Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.56 |
| ▸ | RARG | P13631 | 11/20 | 0.56 |
| ▸ | RARA | P10276 | 10/20 | 0.56 |
| ▸ | RXRA | P19793 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GNG2 | P59768 | 1/20 | 0.37 |
| ▸ | GNB1 | P62873 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109800 | 0.85 | RARB (0.58) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL8101908 | 0.82 | RARB (0.72) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL3456673 | 0.82 | RARB (0.64) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10284325 | 0.81 | RARB (0.60) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL1550094 | 0.79 | CYP3A4 (0.59) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL28971886 | 0.78 | RARA (0.51) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10565430 | 0.78 | RARB (0.70) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7138376 | 0.77 | RARB (0.55) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL27557342 | 0.77 | RARB (0.61) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL27324962 | 0.75 | RARB (0.66) | RARBRARGRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | disclosed |
| WO-1992020643-A1 | NOVEL BI-AROMATIC COMPOUNDS DERIVED FROM A SALICILIC PATTERN, METHOD OF PREPARATION AND USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514264-A1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1992-11-19 | — | — | EP | disclosed |