Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609688 | 0.78 | LMNA (0.47) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL27476915 | 0.75 | LMNA (0.36) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL5609852 | 0.75 | EPHX2 (0.43) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL5609847 | 0.75 | EPHX2 (0.47) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL5609690 | 0.75 | EPHX2 (0.47) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL13994812 | 0.74 | EPHX2 (0.39) | LMNAALDH1A1TSHRHPGDEPHX2 | |
| SCHEMBL8299816 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1TSHRHPGDEPHX2 | |
| Hydrochloric Acid SCHEMBL1677933 | 0.71 | OPRK1 (0.41) | LMNACYP2D6MAPTALDH1A1TSHR | |
| SCHEMBL5253643 | 0.70 | EPHX2 (0.41) | CYP2D6MAPTHPGDEPHX2P2RX7 | |
| SCHEMBL30011388 | 0.70 | SLC22A2 (0.40) | MAPTALDH1A1EPHX2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1354750-A | Amine derivatives compounds | SANKYO CO (JP) | 2002-06-19 | — | — | CN | disclosed |