Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 9/20 | 0.80 |
| ▸ | FDPS | P14324 | 11/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066684 | 0.96 | GGPS1 (0.79) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL15876463 | 0.89 | GGPS1 (1.00) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL10486919 | 0.89 | GGPS1 (1.00) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL7608166 | 0.82 | GGPS1 (0.65) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL8332966 | 0.80 | GGPS1 (0.82) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL15438060 | 0.80 | FDPS (0.54) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL9463628 | 0.77 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL474190 | 0.77 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL21879326 | 0.77 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL20484187 | 0.77 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958618-A | Packaged fabric cleaning compositions | UNILEVER NV | 2013-03-06 | — | — | CN | disclosed |
| CN-1330707-A | Detergent composition | UNILEVER NV (NL) | 2002-01-09 | — | — | CN | disclosed |