SCHEMBL27558406

SCHEMBL27558406

O=CC(=O)c1cc2cccnc2c2ncccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.50
CCR1 P32246 4/20 0.50
CCR8 P51685 4/20 0.50
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
KDM4E B2RXH2 7/20 0.43
KDM6B O15054 1/20 0.43
KDM6A O15550 1/20 0.43
TET3 O43151 1/20 0.43
KDM4A O75164 1/20 0.43
KDM4B O94953 1/20 0.43
KDM5C P41229 1/20 0.43
KDM4D Q6B0I6 1/20 0.43
TET2 Q6N021 1/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
TET1 Q8NFU7 1/20 0.43
FTO Q9C0B1 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27995604 0.88 ALDH1A1 (0.49) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL28056246 0.86 L3MBTL1 (0.43) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL28813948 0.86 KDM4E (0.43) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL28271692 0.84 KDM4E (0.36) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL679992 0.82 KDM4E (0.60) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL11907463 0.81 CCR1 (0.57) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL29089092 0.81 PARP1 (0.60) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL28054321 0.81 KDM4E (0.45) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL13286913 0.80 CCR1 (0.53) L3MBTL1CCR1CCR8ALDH1A1MAPT
SCHEMBL28415920 0.80 KDM4E (0.36) L3MBTL1CCR1CCR8ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057889-B Biotin modified ruthenium (II) complex and preparation method and application thereof 广东药科大学 2024-06-21 CN claimed
CN-116284818-B Photosensitive Co-MOF material and preparation method and application thereof 兰州大学 2024-05-31 CN claimed
CN-117903137-A Butyl tin-cycloiridium phenanthroline complex with AIE characteristics and preparation method and application thereof 曲阜师范大学 2024-04-19 CN claimed
CN-117732509-A Fuel oil catalyst 四川博施来节能技术有限公司 2024-03-22 CN claimed
CN-114409711-B Aptamer-cyclometalated iridium conjugate and preparation method and application thereof 南方海洋科学与工程广东省实验室(湛江) 2024-02-09 CN claimed
CN-117402191-A Lysosome-targeted iridium complex and preparation method and application thereof 温州医科大学慈溪生物医药研究院 2024-01-16 CN claimed
CN-116574138-A Dibromotyrosine-iridium complex and preparation method and application thereof 广东医科大学 2023-08-11 CN claimed
CN-114702492-B Ruthenium (II) -based metal-organic cage compound and preparation method and application thereof 中山大学 2023-07-14 CN claimed
CN-116283984-A Organic thermal delay fluorescent material based on di-tert-butylaniline donor and preparation method thereof 电子科技大学 2023-06-23 CN claimed
CN-115959993-A Synthetic method of 2-aryl propionic acid compound 山东中医药大学 2023-04-14 CN claimed
CN-102276607-B Imidazole [4,5-f]-1,10-phenanthroline derivatives as well as preparation method and application thereof UNIV SHANXI 2012-10-17 CN claimed
CN-1575070-B Organic light emitting device employing doped hole transport layer and/or hole injection layer SAMSUNG MOBILE DISPLAY CO LTD 2012-05-02 CN claimed
CN-102276607-A Imidazole [4,5-f]-1,10-phenanthroline derivatives as well as preparation method and application thereof 2011-12-14 CN claimed
CN-101948488-A Ruthenium-selenium coordination compound and application thereof in preparing fluorescent probe and antineoplastic medicine UNIV JINAN 2011-01-19 CN claimed
CN-100579980-C Ru(II) complex with anticancer liveness and method for preparing the same UNIV SHANXI 2010-01-13 CN claimed
CN-100354270-C Photochromic oxazine compounds and methods for their manufacture JOHNSON & JOHNSON VISION CARE (FR) 2007-12-12 CN claimed
CN-1300146-C Photochromic spiro [ indoline-phenanthroline oxazine ] compound and preparation method and application thereof PHYSICS & CHEMISTRY INST CHINE (CN) 2007-02-14 CN claimed
CN-1612867-A Photochromic oxazine compounds and methods of making the same JOHNSON & JOHNSON VISION CARE (US) 2005-05-04 CN claimed
CN-1583755-A Photochromic spiro [ indoline-phenanthroline oxazine ] compound and preparation method and application thereof PHYSICS & CHEMISTRY INST CHINE (CN) 2005-02-23 CN claimed
CN-1575070-A Organic light-emitting device employing doped hole transporting layer and/or hole injecting layer SAMSUNG SDI CO LTD (KR) 2005-02-02 CN claimed