SCHEMBL28056246

SCHEMBL28056246

O=CC(=O)c1cc2ccc(Cl)nc2c2ncccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
CCR1 P32246 2/20 0.43
CCR8 P51685 2/20 0.43
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 7/20 0.38
EGLN1 Q9GZT9 2/20 0.38
KDM6B O15054 1/20 0.38
KDM6A O15550 1/20 0.38
TET3 O43151 1/20 0.38
KDM4A O75164 1/20 0.38
KDM4B O94953 1/20 0.38
KDM5C P41229 1/20 0.38
KDM4D Q6B0I6 1/20 0.38
TET2 Q6N021 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
TET1 Q8NFU7 1/20 0.38
FTO Q9C0B1 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
KDM3A Q9Y4C1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27558406 0.86 L3MBTL1 (0.50) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL28813948 0.84 KDM4E (0.43) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL28271692 0.82 KDM4E (0.36) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL28054321 0.80 KDM4E (0.45) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL28417245 0.78 KDM4E (0.42) L3MBTL1ALDH1A1KDM4EEGLN1KDM6B
SCHEMBL28415920 0.78 KDM4E (0.36) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL27995604 0.77 ALDH1A1 (0.49) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL28861223 0.74 KDM4E (0.33) L3MBTL1KDM4EEGLN1KDM6BKDM6A
SCHEMBL15688369 0.73 CCR1 (0.51) L3MBTL1CCR1CCR8ALDH1A1KDM4E
SCHEMBL8674711 0.70 KDM4E (0.54) L3MBTL1CCR1CCR8ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104704661-B Electrode active material for electricity storage and electrical storage device 松下电器产业株式会社 2018-05-04 CN disclosed
CN-102666547-B Nitrogen-containing aromatic compound and metal complex SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-05-04 CN disclosed