Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRE | P23469 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310639 | 0.88 | NOTUM (0.53) | NOTUMHTTPTPRCPTPN2PTPN1 | |
| SCHEMBL6312422 | 0.83 | NOTUM (0.49) | NOTUMHTTPTPRCPTPN2PTPN1 | |
| SCHEMBL1082810 | 0.69 | NOTUM (1.00) | NOTUMHTTGPR35SMN1; SMN2MAPT | |
| SCHEMBL2804501 | 0.67 | NOTUM (0.65) | NOTUMHTTSMN1; SMN2 | |
| SCHEMBL31748649 | 0.64 | NOTUM (0.73) | NOTUMHTTSMN1; SMN2MAPT | |
| SCHEMBL9200628 | 0.62 | HTT (0.54) | HTTSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6573412 | 0.62 | NOTUM (0.57) | NOTUMHTTSMN1; SMN2 | |
| SCHEMBL891077 | 0.61 | NOTUM (0.68) | NOTUMHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL23207628 | 0.60 | NR4A2 (0.54) | MAPT | |
| SCHEMBL8444559 | 0.60 | GPR35 (0.37) | NOTUMGPR35NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1300279-A | Modulators of protein tyrosine phosphatases | NOVO NORDISK AS (DK) | 2001-06-20 | — | — | CN | disclosed |