Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.61 |
| ▸ | MEN1 | O00255 | 12/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.56 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311471 | 0.84 | KMT2A (0.64) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL27558689 | 0.83 | GSTO1 (0.63) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL10481224 | 0.81 | KMT2A (0.61) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL10481226 | 0.79 | KMT2A (0.65) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL21259064 | 0.78 | KMT2A (0.63) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL24480003 | 0.78 | KMT2A (0.60) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL21247164 | 0.77 | MEN1 (0.82) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL1799720 | 0.77 | KMT2A (0.61) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL1797300 | 0.77 | KMT2A (0.59) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 | |
| SCHEMBL2368666 | 0.76 | RAB9A (0.55) | KMT2AMEN1GRIN2CRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1300279-A | Modulators of protein tyrosine phosphatases | NOVO NORDISK AS (DK) | 2001-06-20 | — | — | CN | disclosed |