Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.57 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963923 | 0.87 | MEN1 (0.48) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1894620 | 0.84 | MEN1 (0.46) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1907629 | 0.82 | ABL1 (0.56) | KMT2AMEN1MAPTANO1CASP3 | |
| SCHEMBL1954473 | 0.80 | MEN1 (0.55) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1954030 | 0.80 | ANO1 (0.63) | KMT2AMEN1ANO1 | |
| SCHEMBL15258591 | 0.80 | CASP3 (0.56) | KMT2AMEN1RAB9ANPC1NLRP3 | |
| SCHEMBL6311471 | 0.80 | KMT2A (0.64) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12271566 | 0.79 | CASP3 (0.56) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL1954232 | 0.79 | CASP3 (0.52) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1953124 | 0.79 | ANO1 (0.57) | KMT2AMEN1ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | KMT2A 3782/4885MEN1 582/4885RAB9A 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.