Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10239570 | 1.00 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL19413650 | 0.81 | L3MBTL1 (0.41) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL21765383 | 0.78 | GRIN1 (0.43) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL11980107 | 0.78 | HTR6 (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7200967 | 0.76 | LMNA (0.57) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL24622636 | 0.74 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL7075969 | 0.74 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL2751035 | 0.74 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL8597431 | 0.74 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1TSHRNOX1 | |
| SCHEMBL11709981 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1348374-A | Combination preparation of anti-infective active compounds inhibiting the 2-C-methylerythrose-4 metabolic pathway and lipid metabolism inhibitors | JOMAA HASSAN (DE) | 2002-05-08 | — | — | CN | disclosed |