Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365897 | 0.79 | — | — | |
| SCHEMBL7524581 | 0.79 | — | — | |
| SCHEMBL7524506 | 0.79 | — | — | |
| Biphenyl SCHEMBL27509031 | 0.75 | LMNA (0.52) | LMNACYP2D6CYP1A2CYP3A4MAPT | |
| SCHEMBL7575972 | 0.74 | — | — | |
| Biphenyl SCHEMBL27955411 | 0.73 | LMNA (0.50) | LMNACTSCCYP2D6CTSKCYP1A2 | |
| Biphenyl SCHEMBL5180720 | 0.73 | LMNA (0.50) | LMNACTSCCYP2D6CTSKCYP1A2 | |
| Biphenyl SCHEMBL27433633 | 0.72 | ALDH1A1 (0.50) | LMNATSHRCTSKCYP1A2MAPT | |
| SCHEMBL19386831 | 0.72 | FFAR1 (0.46) | LMNATSHRCTSCCYP2D6CTSK | |
| Biphenyl SCHEMBL28026828 | 0.71 | ALDH1A1 (0.56) | LMNATSHRMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422319-C | Method for producing chiral carboxylic acids from nitriles by using nitrilase or nitrilase-containing microorganisms | BASF AG (DE) | 2008-10-01 | — | — | CN | disclosed |
| CN-1331743-A | Method for producing chiral carboxylic acids from nitriles by using nitrilase or nitrilase-containing microorganisms | BASF AG (DE) | 2002-01-16 | — | — | CN | disclosed |