Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23534954 | 0.79 | NUDT1 (0.41) | GRM4NUDT1HSP90AA1 | |
| SCHEMBL29948217 | 0.79 | NUDT1 (0.41) | GRM4NUDT1HSP90AA1 | |
| SCHEMBL22834670 | 0.79 | LMNA (0.40) | GRM4NUDT1HSP90AA1 | |
| SCHEMBL29652037 | 0.79 | LMNA (0.40) | GRM4NUDT1HSP90AA1 | |
| SCHEMBL27559431 | 0.78 | NUDT1 (0.40) | GRM4NUDT1HSP90AA1FGFR1 | |
| SCHEMBL31292534 | 0.77 | KMT2A (0.36) | — | |
| SCHEMBL16659005 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL4736009 | 0.75 | — | — | |
| SCHEMBL16815393 | 0.72 | GAA (0.41) | — | |
| SCHEMBL1590088 | 0.72 | GRM4 (0.47) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1315811-C | Pyrimidine derivatives and preparing method thereof | UNIV NANKAI (CN) | 2007-05-16 | — | — | CN | claimed |
| CN-1528750-A | Pyrimidine derivatives and preparing method thereof | 南开大学 | 2004-09-15 | — | — | CN | claimed |
| CN-1315811-C | Pyrimidine derivatives and preparing method thereof | UNIV NANKAI (CN) | 2007-05-16 | — | — | CN | disclosed |
| CN-1528750-A | Pyrimidine derivatives and preparing method thereof | 南开大学 | 2004-09-15 | — | — | CN | disclosed |