Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559390 | 0.78 | SLC7A5 (0.50) | ALDH1A1GLAHPGDKMT2APTGS1 | |
| SCHEMBL13879329 | 0.77 | DPP4 (0.40) | ALDH1A1GLAHPGDKMT2A | |
| SCHEMBL6224387 | 0.75 | ALDH1A1 (0.48) | ALDH1A1GLAHPGDKMT2A | |
| SCHEMBL3146950 | 0.72 | ALDH1A1 (0.63) | ALDH1A1 | |
| SCHEMBL5721010 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2A | |
| SCHEMBL5721008 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2A | |
| SCHEMBL18557 | 0.71 | LTA4H (0.54) | ALDH1A1GLAHPGD | |
| SCHEMBL17055247 | 0.71 | LTA4H (0.54) | ALDH1A1GLAHPGD | |
| SCHEMBL20547034 | 0.71 | SRD5A2 (0.47) | KMT2A | |
| SCHEMBL20547031 | 0.71 | SRD5A2 (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1297546-C | N- (arylsulfonyl) -beta-amino acid derivatives with substituted aminomethyl group, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2007-01-31 | — | — | CN | disclosed |
| CN-1541211-A | Derivatives of N-(arylsulfonyl) beta-aminoacids comprising substituted aminomethyl group, prepn. method thereof and pharmaceutical compsns. contg same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-10-27 | — | — | CN | disclosed |