Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055247 | 1.00 | LTA4H (0.54) | LTA4HALDH1A1GLAHPGDACHE | |
| SCHEMBL11144165 | 0.92 | ACHE (0.55) | LTA4HALDH1A1GLAHPGDACHE | |
| SCHEMBL10077401 | 0.92 | ACHE (0.55) | LTA4HALDH1A1GLAHPGDACHE | |
| SCHEMBL24200042 | 0.86 | LTA4H (0.47) | LTA4HALDH1A1GLAHPGDACHE | |
| SCHEMBL1488909 | 0.84 | LTA4H (0.45) | LTA4HALDH1A1GLAHPGDACHE | |
| SCHEMBL20811168 | 0.83 | CHRM2 (0.55) | ALDH1A1ACHEPOLBTSHRCHRM2 | |
| SCHEMBL20797832 | 0.83 | CHRM2 (0.55) | ALDH1A1ACHEPOLBTSHRCHRM2 | |
| SCHEMBL16215682 | 0.82 | ALDH1A1 (0.52) | LTA4HALDH1A1ACHEPOLB | |
| SCHEMBL13405849 | 0.82 | ALDH1A1 (0.50) | LTA4HALDH1A1HPGDACHEPOLB | |
| SCHEMBL17533290 | 0.82 | ALDH1A1 (0.44) | LTA4HALDH1A1ACHEPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167867-A1 | SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2022-08-11 | — | — | WO | disclosed |
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |