Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746783 | 0.98 | CRBN (0.66) | CRBNDDB1GAAKDM4EMAPT | |
| SCHEMBL11849406 | 0.96 | CRBN (0.63) | CRBNDDB1GAAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL31439105 | 0.96 | CRBN (0.63) | CRBNDDB1GAAKDM4EMAPT | |
| Glycine SCHEMBL28322063 | 0.84 | DDB1 (0.51) | CRBNDDB1GAAKDM4EMAPT | |
| Phenol SCHEMBL28213597 | 0.83 | KDM4E (0.50) | CRBNDDB1GAAKDM4EMAPT | |
| Benzene SCHEMBL27623238 | 0.80 | KDM4E (0.59) | CRBNDDB1GAAKDM4EMAPT | |
| SCHEMBL62942 | 0.80 | KDM4E (0.59) | CRBNDDB1GAAKDM4EMAPT | |
| SCHEMBL11663462 | 0.80 | DDB1 (0.50) | CRBNDDB1GAAKDM4EMAPT | |
| SCHEMBL8104104 | 0.79 | CRBN (0.67) | CRBNDDB1GAAKDM4EMAPT | |
| SCHEMBL6245696 | 0.78 | CRBN (0.46) | CRBNDDB1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1377282-A | Fatty acid-anticancer conjugates and uses thereof | PROTARGA INC (US) | 2002-10-30 | — | — | CN | disclosed |