SCHEMBL62942

SCHEMBL62942

O=C1CN(c2ccccc2)C(=S)N1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
DDB1 Q16531 1/20 0.50
CRBN Q96SW2 1/20 0.50
GRK5 P34947 1/20 0.46
TYRO3 Q06418 1/20 0.46
DYRK1B Q9Y463 1/20 0.46
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
ALOX5 P09917 2/20 0.43
G6PD P11413 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27623238 1.00 KDM4E (0.59) KDM4EGAAMAPTTDP1DDB1
Alanine SCHEMBL6904189 0.85 GAA (0.45) KDM4EGAAMAPTTDP1DDB1
SCHEMBL14096313 0.83 CTSG (0.45) KDM4EGAAMAPTTDP1CTSG
SCHEMBL746783 0.82 CRBN (0.66) KDM4EGAAMAPTTDP1DDB1
SCHEMBL17082991 0.81 NPC1 (0.47) KDM4EGAAMAPTTDP1NPC1
SCHEMBL1421445 0.81 GAA (0.40) KDM4EGAAMAPTTDP1DDB1
Threonine SCHEMBL7805411 0.81 GAA (0.41) KDM4EGAAMAPTTDP1DDB1
Hydrochloric Acid SCHEMBL31439105 0.80 CRBN (0.63) KDM4EGAAMAPTTDP1DDB1
SCHEMBL11849406 0.80 CRBN (0.63) KDM4EGAAMAPTTDP1DDB1
SCHEMBL27560841 0.80 CRBN (0.63) KDM4EGAAMAPTTDP1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2457 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573372-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-06-25 EP claimed
EP-4555134-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-05-21 EP claimed
WO-2025064836-A2 AMINO ACID BINDING AGENTS AND THEIR USES GLYPHIC BIOTECHNOLOGIES, INC. (US) 2025-03-27 WO claimed
US-12188940-B2 Determination of protein information by recoding amino acid polymers into DNA polymers ABRUS BIO, INC. (US) 2025-01-07 US claimed
US-20240210410-A1 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS ABRUS BIO, INC. 2024-06-27 US claimed
WO-2024040236-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS ABRUS BIO, INC. (US) 2024-02-22 WO claimed
WO-2024015875-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS ABRUS BIO, INC. (US) 2024-01-18 WO claimed
CN-110369712-B Preparation method of silver-coated copper powder 嘉兴学院 2021-08-20 CN claimed
CN-108299086-A A kind of gardenia mill water culture nutrient solution 平南县德湖种养农民专业合作社 2018-07-20 CN claimed
US-20120157658-A1 METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS JOHNSON THOMAS E (US) 2012-06-21 US claimed
US-5270213-A Protein sequencing PORTON INSTRUMENTS, INC. (US) 1993-12-14 US claimed
EP-0549752-A1 PROTEIN SEQUENCING BECKMAN INSTRUMENTS, INC. (US) 1993-07-07 EP claimed
EP-0368920-B1 LECTINES FIXING BETA-D-GALACTOSIDE INCYTE PHARMACEUTICALS, INC. (US) 1993-06-09 EP claimed
WO-1993000355-A1 PROTEIN SEQUENCING PORTON INSTRUMENTS, INC. (US) 1993-01-07 WO claimed
US-5143851-A METHOD FOR SEPARATING DIPHENYLUREA (DPU) AND PHENYLTHIOHYDANTOIN-TRYPTOPHAN (PTH-TRP) ALLOWING UNAMBIGUOUS IDENTIFICATION OF TRP IN AUTOMATIC SEQUENCE ANALYSIS AMERICAN CYANAMID COMPANY (US) 1992-09-01 US claimed
WO-1992000526-A1 PEPTIDE SEQUENCING METHOD AND REAGENTS THEREFOR GARIEPY KATHLEEN COX (US) 1992-01-09 WO claimed
EP-0447746-A1 A method for separating Diphenylurea(DPU) and phenylthiohydantoin-tryptophan (PTH-TRP) allowing unambiguous indentification of TRP in automatic sequence analysis AMERICAN CYANAMID COMPANY (US) 1991-09-25 EP claimed
US-5019348-A Automated chemical conversion unit in a peptide/protein sequenator BECKMAN INSTRUMENTS, INC. (US) 1991-05-28 US claimed
EP-0368920-A1 LECTINES FIXING BETA-D-GALACTOSIDE. IDEON CORP (US) 1990-05-23 EP claimed
WO-1989000581-A1 LECTINES FIXING BETA-D-GALACTOSIDE IDEON CORPORATION (US) 1989-01-26 WO claimed