SCHEMBL746783

SCHEMBL746783

O=C1CN(c2ccccc2)C(=O)N1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 7/20 0.66
DDB1 Q16531 6/20 0.66
GAA P10253 2/20 0.66
KDM4E B2RXH2 1/20 0.66
MAPT P10636 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PTPN1 P18031 1/20 0.44
ALOX5 P09917 2/20 0.42
G6PD P11413 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
CTSG P08311 1/20 0.41
CMA1 P23946 1/20 0.41
GSK3A P49840 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31439105 0.98 CRBN (0.63) CRBNDDB1GAAKDM4EMAPT
SCHEMBL11849406 0.98 CRBN (0.63) CRBNDDB1GAAKDM4EMAPT
SCHEMBL62942 0.82 KDM4E (0.59) CRBNDDB1GAAKDM4EMAPT
SCHEMBL11663462 0.82 DDB1 (0.50) CRBNDDB1GAAKDM4EMAPT
SCHEMBL8104104 0.81 CRBN (0.67) CRBNDDB1GAAKDM4EMAPT
SCHEMBL10192194 0.79 MAPT (0.53) CRBNDDB1GAAKDM4EMAPT
SCHEMBL10813665 0.79 MEN1 (0.53) CRBNDDB1GAAKDM4EMAPT
SCHEMBL6245696 0.79 CRBN (0.46) CRBNDDB1GAAKDM4EMAPT
SCHEMBL1421342 0.79 DDB1 (0.46) CRBNDDB1GAAKDM4EMAPT
SCHEMBL4539723 0.79 CRBN (0.46) CRBNDDB1GAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118904163-A Preparation method and device for preparing phenylglycine by using pipelining continuous flow 海连化工科技(绍兴)有限公司 2024-11-08 CN claimed
CN-118667895-A Improved production process of p-hydroxyphenylglycine by enzyme method 联邦制药(内蒙古)有限公司 2024-09-20 CN claimed
CN-220664953-U Mother liquor recycling system for phenylhydantoin production 内蒙古天宇达生物科技有限公司 2024-03-26 CN claimed
CN-111847446-B Aza-hybridized mesoporous carbon and preparation method thereof 天津市职业大学 2023-05-26 CN claimed
CN-110330460-B Preparation method of p-hydroxy-phenyl-hydantoin 中国科学技术大学 2023-02-21 CN claimed
CN-218306256-U High-efficient crystallization kettle device is used in production of benzene hydantoin 内蒙古天宇达生物科技有限公司 2023-01-17 CN claimed
CN-111269134-B Preparation method of phenylglycine and derivatives thereof 九江中星医药化工有限公司 2022-09-20 CN claimed
CN-114766503-A Preparation and application methods of bactericide for reverse osmosis system 上海循诺环保科技有限公司 2022-07-22 CN claimed
CN-113801064-A Method for constructing phenylhydantoin by [3+2] cycloaddition reaction 甘肃省化工研究院有限责任公司 2021-12-17 CN claimed
CN-113636682-A Method for treating high-concentration organic waste liquid and co-producing lithium iron phosphate battery material 天津市职业大学 2021-11-12 CN claimed
CN-102333526-A Fast dissolving oral film dosage comprising stevioside as an unpleasant taste masking agent BEXCORE INC 2012-01-25 CN claimed
CN-1829490-A Films comprising therapeutic agents TODD MAIBACH (US) 2006-09-06 CN claimed
US-6232059-B1 ORGANIC SILVER SALT, A REDUCING AGENT, AND A SPECIFIC NUCLEATING AGENT; HIGH DMAX, HIGH SENSITIVITY, SATISFACTORY CONTRAST, LOW FOG, AND MINIMAL DEPENDENCY OF PHOTOGRAPHIC PROPERTIES ON DEVELOPING TEMPERATURE FUJI PHOTO FILM CO., LTD. (JP) 2001-05-15 US claimed
US-5763191-A BINDING MATRIX BOEHRINGER MANNHEIM GMBH (DE) 1998-06-09 US claimed
US-4898860-A Anticonvulsant composition and method NEW YORK UNIVERSITY (US) 1990-02-06 US claimed
US-4672101-A Polyepoxy aromatic hydantoins THE DOW CHEMICAL COMPANY (US) 1987-06-09 US claimed
US-4436877-A HYDANTOIN TO RETARD EVOLUTION OF AROMATIC DIACID VAPORS DURING MELT PROCESSING POLYPLASTICS CO., LTD. (JP) 1984-03-13 US claimed
US-4304782-A ANNATO, PAPRIKA, CARROT OIL, YELLOW VEGETABLE OIL REGION WALLONNE (BE) 1981-12-08 US claimed
EP-0015038-A1 Pharmaceutical composition containing a diphenylhydantoin derivative, derivatives used and their preparation REGION WALLONNE représentée par le Ministre des Technologies nouvelles de la region wallonne (BE) 1980-09-03 EP claimed
US-4094741-A CULTURES, ASYMMETRIC HYDROLYSIS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1978-06-13 US claimed