Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582471 | 0.94 | TAAR1 (0.60) | TAAR1AOC3CALM1CAMKK2CYP2D6 | |
| SCHEMBL27553988 | 0.82 | TAAR1 (0.50) | TAAR1AOC3CALM1CAMKK2CYP2D6 | |
| SCHEMBL21594142 | 0.80 | TAAR1 (0.63) | TAAR1AOC3CALM1CAMKK2CYP2D6 | |
| SCHEMBL26628603 | 0.80 | TAAR1 (0.63) | TAAR1AOC3CALM1CAMKK2CYP2D6 | |
| SCHEMBL26613652 | 0.80 | TAAR1 (0.63) | TAAR1AOC3CALM1CAMKK2CYP2D6 | |
| SCHEMBL28137582 | 0.74 | TAAR1 (0.55) | TAAR1AOC3MAOBCALM1CAMKK2 | |
| SCHEMBL11775034 | 0.73 | LTA4H (0.67) | SLC6A4CYP2D6ALDH1A1HTT | |
| SCHEMBL3235280 | 0.73 | TAAR1 (0.47) | TAAR1MAOBSLC6A4LMNATP53 | |
| SCHEMBL9416597 | 0.73 | ACHE (0.59) | AOC3MAOBCALM1CAMKK2IDO1 | |
| SCHEMBL7120894 | 0.73 | MEN1 (0.54) | MAOBLMNAMAPTCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1373745-A | 3-amino-2-benzyl-1-phenyl-propane derivs. | GREULENTHAL GMBH (DE) | 2002-10-09 | — | — | CN | claimed |
| CN-1369011-A | Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines | US GOV HEALTH & HUMAN SERV (US) | 2002-09-11 | — | — | CN | disclosed |