Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219106 | 0.75 | SLC6A4 (0.59) | TAAR1SLC6A4ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL28978069 | 0.74 | TAAR1 (0.63) | TAAR1MAOB | |
| SCHEMBL3235287 | 0.73 | LDHA (0.44) | SLC6A4KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL27561802 | 0.73 | TAAR1 (0.54) | TAAR1SLC6A4MAOBSLC2A1KDM4E | |
| SCHEMBL10289884 | 0.72 | KDM4E (0.53) | BCHEMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14402689 | 0.70 | CETP (0.41) | TAAR1TDP1 | |
| SCHEMBL11775034 | 0.70 | LTA4H (0.67) | SLC6A4ALDH1A1HTT | |
| SCHEMBL3179539 | 0.70 | TAAR1 (0.62) | TAAR1 | |
| SCHEMBL16235822 | 0.70 | SLC6A4 (0.53) | TAAR1SLC6A4MAOB | |
| SCHEMBL345525 | 0.70 | LDHA (0.53) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |