Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.47 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.46 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747314 | 0.95 | SLC20A2 (0.47) | CCR9SLC10A2SLC10A1SLC10A6SLC20A2 | |
| SCHEMBL27561845 | 0.93 | SLC10A6 (0.54) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL27544069 | 0.93 | SLC20A2 (0.56) | CCR9SLC10A2SLC10A1SLC10A6SLC20A2 | |
| SCHEMBL27561909 | 0.91 | SLC10A6 (0.48) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL27542769 | 0.90 | CCR9 (0.47) | CCR9SLC10A2SLC10A1SLC10A6SLC20A2 | |
| SCHEMBL27540995 | 0.90 | SLC10A2 (0.48) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL27576901 | 0.90 | SLC10A2 (0.48) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL28941326 | 0.90 | SLC10A6 (0.58) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL27576899 | 0.90 | SLC10A6 (0.48) | CCR9SLC10A2SLC10A1SLC10A6MEN1 | |
| SCHEMBL27571188 | 0.88 | MEN1 (0.47) | SLC10A2SLC10A1SLC10A6SLC20A2SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1332943-C | Sulfur-substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMACEUTICALS AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| CN-1308606-A | Sulfur-substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMACEUTICALS AG (DE) | 2001-08-15 | — | — | CN | disclosed |