Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561882 | 0.74 | LMNA (0.47) | LMNAKMT2AMEN1GAACA1 | |
| SCHEMBL4557719 | 0.72 | CYP2C19 (0.43) | LMNACYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27617107 | 0.71 | CA1 (0.46) | LMNACA1CA2CA12CA9 | |
| SCHEMBL27582572 | 0.71 | CA1 (0.46) | KMT2ACA1CA2CA12CA9 | |
| Acetic Acid SCHEMBL9574999 | 0.69 | ALDH1A1 (0.45) | LMNACYP1A2CYP2D6KMT2AGAA | |
| SCHEMBL6639307 | 0.69 | LMNA (0.42) | LMNACYP2D6GAACA1CA2 | |
| SCHEMBL27995434 | 0.69 | CTSD (0.50) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL28352597 | 0.68 | LMNA (0.53) | LMNACYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL4224462 | 0.68 | CYP2C19 (0.55) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL7574319 | 0.67 | MTOR (0.43) | LMNANPSR1KMT2AGAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1404829-A | Double inhibitor synthesized by wax ester and cholesterol ester for inbibiting generation of sebum | WARNER LAMBERT CO (US) | 2003-03-26 | — | — | CN | claimed |
| CN-1370526-A | Treating method of nuclear factor-KB mediated diseases and dysfuction | WANER LONGBER CO (US) | 2002-09-25 | — | — | CN | claimed |
| CN-1404829-A | Double inhibitor synthesized by wax ester and cholesterol ester for inbibiting generation of sebum | WARNER LAMBERT CO (US) | 2003-03-26 | — | — | CN | disclosed |
| CN-1370526-A | Treating method of nuclear factor-KB mediated diseases and dysfuction | WANER LONGBER CO (US) | 2002-09-25 | — | — | CN | disclosed |