Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27563188 | 0.92 | PLA2G2A (0.41) | PLA2G2AHTT | |
| SCHEMBL27530210 | 0.90 | GPR52 (0.38) | PLA2G2APOLBMAPK8L3MBTL1SCN9A | |
| SCHEMBL27530259 | 0.89 | IDO1 (0.40) | ALDH1A1SMN1; SMN2HTTPOLBFABP4 | |
| SCHEMBL27505260 | 0.88 | MAPK8 (0.38) | SMN1; SMN2MAPTHTTPOLBMAPK8 | |
| SCHEMBL27507171 | 0.88 | ABCC1 (0.42) | PLA2G2AMAPK8L3MBTL1CYP3A4ABCC1 | |
| SCHEMBL27525956 | 0.87 | PLA2G1B (0.47) | PLA2G2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL27505576 | 0.87 | GPR52 (0.39) | HTTL3MBTL1CYP3A4ABCC1 | |
| SCHEMBL27530677 | 0.87 | PLA2G10 (0.42) | FABP4L3MBTL1 | |
| SCHEMBL27530143 | 0.86 | PLA2G2A (0.42) | PLA2G2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL27530159 | 0.86 | PARP15 (0.41) | POLBMAPK8L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240210-A | Substituted tricyclic compound | LILLY CO ELI (US) | 2000-01-05 | — | — | CN | disclosed |