Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 14/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27563128 | 0.92 | PLA2G2A (0.41) | PLA2G2AHTT | |
| SCHEMBL27525956 | 0.90 | PLA2G1B (0.47) | PLA2G2AADRA1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28740781 | 0.90 | SIRT2 (0.43) | PLA2G2A | |
| SCHEMBL27530677 | 0.90 | PLA2G10 (0.42) | ADRA1DPARP1PLA2G10PLA2G1B | |
| SCHEMBL27530259 | 0.90 | IDO1 (0.40) | PARP1HTT | |
| SCHEMBL27568366 | 0.90 | PLA2G10 (0.43) | PLA2G2AADRA1DPLA2G10 | |
| SCHEMBL27506748 | 0.89 | PLA2G2A (0.41) | PLA2G2AADRA1DPARP1CYP1A2CYP2C9 | |
| SCHEMBL27530159 | 0.89 | PARP15 (0.41) | PARP1PLA2G1B | |
| SCHEMBL27530210 | 0.89 | GPR52 (0.38) | PLA2G2APARP1PLA2G10PLA2G1B | |
| SCHEMBL27526164 | 0.88 | FABP4 (0.38) | PLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240210-A | Substituted tricyclic compound | LILLY CO ELI (US) | 2000-01-05 | — | — | CN | disclosed |