Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590504 | 0.92 | CA5A (0.38) | CYP3A4ABCC1CA5AOPRM1OPRD1 | |
| SCHEMBL27530595 | 0.89 | GPR52 (0.37) | CYP3A4ABCC1SCN9APARP1LMNA | |
| SCHEMBL27505187 | 0.88 | MAPK14 (0.33) | CYP3A4ABCC1SCN9AMAPK14GPR52 | |
| SCHEMBL27525922 | 0.88 | AKR1B10 (0.32) | CYP3A4ABCC1CA5ASCN9APARP1 | |
| SCHEMBL27530519 | 0.87 | SCN9A (0.33) | CYP3A4ABCC1SCN9APARP1MEN1 | |
| SCHEMBL27506428 | 0.87 | AURKA (0.41) | CYP3A4ABCC1SCN9APARP1MAPK8 | |
| SCHEMBL27505648 | 0.87 | ABCC1 (0.36) | CYP3A4ABCC1CA5ASCN9APARP1 | |
| SCHEMBL27505972 | 0.87 | CYP3A4 (0.33) | CYP3A4ABCC1CA5AMEN1LMNA | |
| SCHEMBL28740750 | 0.86 | KMT2A (0.34) | CYP3A4ABCC1MEN1LMNAXBP1 | |
| SCHEMBL28740784 | 0.86 | PDE4A (0.32) | CYP3A4ABCC1CA5ASCN9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240210-A | Substituted tricyclic compound | LILLY CO ELI (US) | 2000-01-05 | — | — | CN | disclosed |