Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9032205 | 0.84 | HTR1A (0.57) | HTR1ASLC6A4HTR2ADRD2HTR7 | |
| SCHEMBL7461768 | 0.81 | HTR1A (0.60) | HTR1ASLC6A4DRD3DRD2ADRA1D | |
| SCHEMBL14306777 | 0.81 | ADRA1D (0.80) | SLC6A4ADRA1DCYP2D6 | |
| SCHEMBL8554480 | 0.78 | HTR1A (0.77) | HTR1ASLC6A4HTR2ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL9029293 | 0.78 | ADRA1D (0.60) | HTR1ASLC6A4HTR2ADRD2HTR7 | |
| SCHEMBL8555335 | 0.78 | HTR1A (0.67) | HTR1ASLC6A4HTR2ADRD3DRD2 | |
| SCHEMBL8555085 | 0.77 | HTR1A (0.73) | HTR1ASLC6A4HTR2ADRD2HTR7 | |
| SCHEMBL11113767 | 0.77 | GAA (0.59) | HTR1ASLC6A4 | |
| SCHEMBL4468600 | 0.76 | ADRA1D (0.72) | SLC6A4ADRA1DCYP2D6 | |
| SCHEMBL8558005 | 0.76 | HTR1A (0.77) | HTR1ASLC6A4HTR2ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1307573-A | Indolyl derivatives and serotonergic agents | AMERICAN HOME PROD (US) | 2001-08-08 | — | — | CN | claimed |