Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637682 | 0.88 | SNCA (0.66) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL2582828 | 0.88 | SNCA (0.66) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL29640485 | 0.88 | MAPT (0.59) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL225916 | 0.88 | MAPT (0.59) | SNCAMAPTNOX1MEN1KMT2A | |
| Bromide SCHEMBL30448580 | 0.86 | SNCA (0.64) | SNCAMAPTNOX1MEN1KMT2A | |
| Bromide SCHEMBL20495634 | 0.86 | SNCA (0.64) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL30065446 | 0.81 | SNCA (0.58) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL205578 | 0.81 | SNCA (0.58) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL2756476 | 0.81 | NOX1 (0.53) | SNCAMAPTNOX1MEN1KMT2A | |
| SCHEMBL239549 | 0.79 | NOX1 (0.65) | SNCAMAPTNOX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994017095-A1 | ANALOGS OF RECEPTOR TYROSINE ACTIVATION MOTIFS AND THERAPEUTIC USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |