SCHEMBL2756715

SCHEMBL2756715

CC1=Cc2sc(C)cc2C1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6518706 0.84
SCHEMBL15980346 0.80 PNMT (0.37) PNMT
SCHEMBL22503335 0.78 PNMT (0.32) PNMT
SCHEMBL17339848 0.76 PNMT (0.36) PNMT
SCHEMBL13183593 0.65 PNMT (0.48) PNMT
SCHEMBL19122298 0.65
SCHEMBL24960502 0.65 ALDH1A1 (0.30)
SCHEMBL22601014 0.65 ALDH1A1 (0.30)
SCHEMBL15274297 0.64
SCHEMBL2917929 0.64 PNMT (0.34) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082363-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE Basell Polyolefine GmbH (DE) 2001-03-14 EP claimed
WO-2000044799-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE TARGOR GMBH (DE) 2000-08-03 WO claimed
EP-3024040-B1 ORGANIC FILM TRANSISTOR, ORGANIC SEMICONDUCTOR FILM, AND ORGANIC SEMICONDUCTOR MATERIAL AND USE APPLICATIONS THEREOF FUJIFILM CORP (JP) 2019-05-08 EP disclosed
US-9511056-B2 Antiviral compounds GILEAD PHARMASSET LLC (US) 2016-12-06 US disclosed
US-9120779-B2 Inhibitors of HCV NS5A PRESIDIO PHARMACEUTICALS, INC. (US) 2015-09-01 US disclosed
US-20150232455-A1 ANTI-VIRAL COMPOUNDS ABBVIE INC. 2015-08-20 US disclosed
US-20150158909-A1 ANTI-VIRAL COMPOUNDS ABBVIE INC. 2015-06-11 US disclosed
US-20150057218-A1 INHIBITORS OF HCV NS5A PRESIDIO PHARMACEUTICALS INC (US) 2015-02-26 US disclosed
US-20150038501-A1 INHIBITORS OF HCV NS5A PRESIDIO PHARMACEUTICALS, INC. 2015-02-05 US disclosed
US-8921369-B2 Inhibitors of HCV NS5A PRESIDIO PHARMACEUTICALS, INC. (US) 2014-12-30 US disclosed
US-8877707-B2 Inhibitors of HCV NS5A PRESIDIO PHARMACEUTICALS, INC. (US) 2014-11-04 US disclosed
WO-2001048035-A2 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed
EP-1082363-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE Basell Polyolefine GmbH (DE) 2001-03-14 EP disclosed
EP-1054914-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND Basell Polyolefine GmbH (DE) 2000-11-29 EP disclosed
WO-2000064906-A1 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2000-11-02 WO disclosed
WO-2000062928-A1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2000-10-26 WO disclosed
WO-2000020466-A9 CATALYST SYSTEM TARGOR GMBH (DE) 2000-09-21 WO disclosed
WO-2000044799-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE TARGOR GMBH (DE) 2000-08-03 WO disclosed
WO-2000035973-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND WHICH CONTAINS BORON TARGOR GMBH (DE) 2000-06-22 WO disclosed
WO-2000018773-A1 CHEMICAL COMPOUND TARGOR GMBH (DE) 2000-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150232455-A1 ANTI-VIRAL COMPOUNDS HAVCR2, EIF2AK2, MAVS PNMT 2207/4885
US-20150057218-A1 INHIBITORS OF HCV NS5A HAVCR2, MAVS, EIF2AK2 PNMT 3973/4885
US-20150038501-A1 INHIBITORS OF HCV NS5A HAVCR2, MAVS, EIF2AK2 PNMT 3973/4885
US-20150158909-A1 ANTI-VIRAL COMPOUNDS HAVCR2, EIF2AK2, MAVS PNMT 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.