SCHEMBL2756825

SCHEMBL2756825

C=CC(=O)Oc1c(CCCC)cc(C)cc1C(C)c1cc(C)cc(CCCC)c1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 4/20 0.40
▸ THRA P10827 2/20 0.40
▸ HPGD P15428 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ EGFR P00533 1/20 0.32
▸ FFAR1 O14842 1/20 0.32
▸ TSHR P16473 1/20 0.31
▸ ALOX5 P09917 2/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2756823 0.89 THRB (0.43) THRBTHRAHPGDEGFRTSHR
SCHEMBL2756821 0.88 THRB (0.40) THRBTHRAHPGDEGFRTSHR
SCHEMBL12393875 0.86 THRB (0.48) THRBTHRAALOX5CNR2
SCHEMBL2756822 0.84 THRB (0.35) THRBTHRA
SCHEMBL2756824 0.83 THRB (0.36) THRBTHRACNR2
SCHEMBL12449961 0.83 THRB (0.38) THRBTHRAHPGDALDH1A1KDM4E
SCHEMBL26665398 0.83 THRB (0.51) THRBTHRAHPGDALDH1A1KDM4E
SCHEMBL10154168 0.81 THRB (0.43) THRBTHRAHPGDALDH1A1KDM4E
SCHEMBL12166734 0.81 THRB (0.49) THRBTHRAHPGDALDH1A1KDM4E
SCHEMBL3807221 0.80 TYR (0.40) HPGDALDH1A1KDM4EHSD17B10EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220195142-A1 POLYOLEFIN RESIN COMPOSITION AND PRODUCTION METHOD THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-06-23 — — US disclosed
US-8274625-B2 Cellulose ester film, method for production of cellulose ester film, and protective film for polarizing plate, polarizing plate and liquid crystal display device each using the cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2012-09-25 — — US disclosed
US-8088831-B2 Cellulose ester film, method for producing cellulose ester film, polarizing plate using the same, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-01-03 — — US disclosed
US-20100188622-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCTION OF CELLULOSE ESTER FILM, AND PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EACH USING THE CELLULOSE ESTER FILM KONICA MINOLTA OPTO, INC. (JP) 2010-07-29 — — US disclosed
US-20100182548-A1 CELLULOSE ESTER FILM, METHOD FOR PRODUCING CELLULOSE ESTER FILM, POLARIZING PLATE USING THE SAME, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-07-22 — — US disclosed
US-20090155495-A1 PROCESS FOR PRODUCING CELLULOSE ACYLATE FILM, CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID-CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2009-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220195142-A1 POLYOLEFIN RESIN COMPOSITION AND PRODUCTION METHOD THEREOF PUF60, MACF1, ACR THRB 3490/4885THRA 2918/4885HPGD 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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