SCHEMBL9723653

SCHEMBL9723653

O=C(OF)C(F)(C(=O)OF)C(c1ccccc1)(c1ccccc1)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.43
LMNA P02545 4/20 0.43
S1PR4 O95977 2/20 0.43
S1PR1 P21453 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
KCNN4 O15554 3/20 0.40
PTPN1 P18031 1/20 0.38
TSHR P16473 1/20 0.37
MAOB P27338 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CES1 P23141 2/20 0.35
CYP1A2 P05177 1/20 0.35
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27568720 0.79 KCNN4 (0.44) MAPTALDH1A1LMNAS1PR4S1PR1
SCHEMBL2451645 0.76 KCNN4 (0.45) MAPTALDH1A1LMNAKCNN4PTPN1
SCHEMBL29095960 0.75 KCNN4 (0.44) MAPTALDH1A1LMNAKCNN4PTPN1
Hydrochloric Acid SCHEMBL29145555 0.75 KCNN4 (0.44) MAPTALDH1A1LMNAKCNN4PTPN1
SCHEMBL5054007 0.74 KCNN4 (0.40) MAPTALDH1A1LMNAS1PR4S1PR1
SCHEMBL8583194 0.73 KCNN4 (0.42) MAPTALDH1A1LMNAKCNN4PTPN1
SCHEMBL28049560 0.72 CHRM3 (0.46) MAPTALDH1A1LMNAKCNN4KMT2A
SCHEMBL612731 0.72 ALDH1A1 (0.58) MAPTALDH1A1LMNAS1PR4S1PR1
Ammonia Solution, Strong SCHEMBL7131897 0.70 TSHR (0.55) MAPTALDH1A1LMNAS1PR4S1PR1
SCHEMBL9290961 0.69 SRD5A2 (0.55) PTPN1TSHRESR1ESR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112924-A Multilayer fabric, fiber or particle composite of improved heat resistance and high strength HERCULES INCORPORATED (US) 1992-05-12 US disclosed
US-5096766-A Prepregs HERCULES INCORPORATED (US) 1992-03-17 US disclosed
US-4946908-A DAMAGE TOLERANCE, SHEAR STRENGTH, THERMOCRACKING HERCULES INCORPORATED (US) 1990-08-07 US disclosed
EP-0363524-A1 Bismaleimide compositions containing high glass transition temperature and soluble reactive oligomers and composites prepared therefrom HERCULES INCORPORATED (US) 1990-04-18 EP disclosed
EP-0319008-A2 Epoxy resin compositions as used in producing composites with high wet glass transition temperatures and in adhesive applications HERCULES INCORPORATED (US) 1989-06-07 EP disclosed