Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | GNG2 | P59768 | 2/20 | 0.37 |
| ▸ | GNB1 | P62873 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696297 | 0.77 | RAPGEF4 (0.68) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10630409 | 0.77 | ALDH1A1 (0.40) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL866958 | 0.75 | RAPGEF4 (1.00) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29319990 | 0.75 | RAPGEF4 (0.71) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29516556 | 0.75 | RAPGEF4 (1.00) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27757536 | 0.75 | CA1 (0.37) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL7551968 | 0.74 | RAPGEF4 (0.97) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8652689 | 0.74 | RAPGEF4 (0.97) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9189649 | 0.73 | RAPGEF4 (0.97) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10911901 | 0.72 | RAPGEF4 (0.57) | RAPGEF4MAPTALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1325380-A | Benzene derivatives and medical use thereof | AJINOMOTO KK (JP) | 2001-12-05 | — | — | CN | disclosed |