Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531827 | 0.83 | GPR17 (0.42) | GPR17ALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6510028 | 0.83 | GPR17 (0.73) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL27569328 | 0.73 | ALDH1A1 (0.52) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL840736 | 0.71 | GPR84 (0.65) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL29623480 | 0.71 | GPR84 (0.65) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL27533852 | 0.71 | ALDH1A1 (0.52) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL9755961 | 0.69 | ALDH1A1 (0.58) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL10719605 | 0.69 | KDM4E (0.56) | GPR17ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL5694486 | 0.68 | ALDH1A1 (0.69) | ALDH1A1KDM4EMEN1POLBGAA | |
| SCHEMBL2673123 | 0.68 | KDM4E (0.55) | GPR17ALDH1A1KDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | claimed |
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | disclosed |