Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27572548 | 0.92 | CDK2 (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL27574287 | 0.91 | CCNE1 (0.37) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL7257113 | 0.89 | CDK2 (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL6710898 | 0.88 | MLYCD (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL6711707 | 0.88 | MLYCD (0.47) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL27574281 | 0.87 | CDK2 (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL27551074 | 0.86 | CDK2 (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL27551031 | 0.86 | CDK2 (0.38) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL6715792 | 0.85 | MAPT (0.41) | CDK2CCNE1CDK5MLYCDALOX5 | |
| SCHEMBL27574286 | 0.85 | MLYCD (0.39) | CDK2CCNE1CDK5MLYCDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1325390-A | 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | CN | claimed |
| CN-1325390-A | 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | CN | disclosed |