Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570743 | 0.86 | VNN1 (0.37) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL6711844 | 0.85 | CCNE1 (0.35) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27572548 | 0.85 | CDK2 (0.38) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27570619 | 0.85 | CDK2 (0.38) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27574287 | 0.84 | CCNE1 (0.37) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL6711707 | 0.83 | MLYCD (0.47) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27574281 | 0.82 | CDK2 (0.38) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27551074 | 0.82 | CDK2 (0.38) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL27551031 | 0.81 | CDK2 (0.38) | MLYCDCCNE1CDK2CDK5ALOX5 | |
| SCHEMBL6715792 | 0.81 | MAPT (0.41) | MLYCDCCNE1CDK2CDK5ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1325390-A | 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | CN | claimed |
| CN-1325390-A | 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | CN | disclosed |