Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | RARB | P10826 | 8/20 | 0.54 |
| ▸ | RARA | P10276 | 2/20 | 0.54 |
| ▸ | LPL | P06858 | 2/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RARG | P13631 | 1/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126881 | 0.93 | LPL (0.56) | PPARAPPARGRARBRARALPL | |
| SCHEMBL27694667 | 0.93 | LPL (0.56) | PPARAPPARGRARBRARALPL | |
| SCHEMBL6059834 | 0.92 | LPL (0.54) | PPARAPPARGRARBLPLLIPG | |
| SCHEMBL5551488 | 0.90 | LPL (0.53) | PPARAPPARGLPLLIPG | |
| Phthalic Acid SCHEMBL27978921 | 0.89 | PPARA (0.58) | PPARAPPARGRARBRARALPL | |
| SCHEMBL28079356 | 0.88 | LPL (0.61) | PPARAPPARGLPLLIPGALDH1A1 | |
| SCHEMBL11515483 | 0.86 | PSMB5 (0.49) | RARBLPLLIPG | |
| SCHEMBL30500519 | 0.86 | PSMB5 (0.49) | RARBLPLLIPG | |
| SCHEMBL9658657 | 0.86 | LPL (0.59) | PPARAPPARGLPLLIPG | |
| Bicarbonate SCHEMBL27817579 | 0.85 | RARB (0.73) | RARBRARAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448912-C | Method for producing polyester carbonic ester | BAYER AG (DE) | 2009-01-07 | — | — | CN | claimed |
| CN-1412219-A | Method for producing polyester carbonic ester | BAYER AG (DE) | 2003-04-23 | — | — | CN | claimed |
| CN-102093684-B | Polycarbonate Alloys with highly resistance deformability and improved surface property | 科思创德国股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-108778766-A | Method for carrying out part dyeing to plastic part | 科思创德国股份有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-105189604-B | The production of makrolon with limited metal residue | 沙特基础全球技术有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-107207846-A | The copolycarbonate composition for including double glyceride with improved rheology and optical property | 科思创德国股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107207845-A | Copolycarbonate compositions comprising PE-waxes with improved processability | 科思创德国股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107075103-A | The method that makrolon is manufactured using liquid alcohol/ketone mixtures | 沙特基础工业全球技术有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104136508-B | Prepare for the method with low stress and the film of optical property in photoelectric device | 科思创德国股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-104231254-B | For the method producing polycarbonate compositions | 沙特基础全球技术有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105473223-A | Heterogeneous catalysts for the transesterification of aromatic alcohols; and methods of making and use thereof | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-06 | — | — | CN | disclosed |
| CN-104231254-A | Process for the manufacture of polycarbonate compositions | SABIC INNOVATIVE PLASTICS IP | 2014-12-24 | — | — | CN | disclosed |
| CN-104136508-A | Process for the production of low stress and optical quality film for use in opto-electronic devices | BAYER MATERIALSCIENCE AG | 2014-11-05 | — | — | CN | disclosed |
| CN-102356112-A | Copolycarbonates with improved properties | BAYER MATERIALSCIENCE AG | 2012-02-15 | — | — | CN | disclosed |
| CN-102227463-A | Copolycarbonates with improved surface hardness | BAYER MATERIALSCIENCE AG | 2011-10-26 | — | — | CN | disclosed |
| CN-102224010-A | Security feature in security or value documents | BAYER MATERIALSCIENCE AG | 2011-10-19 | — | — | CN | disclosed |
| CN-102196920-A | ID card with laser engraving resistance | BAYER MATERIALSCIENCE AG | 2011-09-21 | — | — | CN | disclosed |
| CN-102164753-A | Use of plastic films in colour laser printing | BAYER MATERIALSCIENCE AG | 2011-08-24 | — | — | CN | disclosed |
| CN-100448912-C | Method for producing polyester carbonic ester | BAYER AG (DE) | 2009-01-07 | — | — | CN | disclosed |
| CN-1412219-A | Method for producing polyester carbonic ester | BAYER AG (DE) | 2003-04-23 | — | — | CN | disclosed |