Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 4/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569468 | 0.79 | TYK2 (0.36) | KDM4EALDH1A1TYK2 | |
| SCHEMBL27298339 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6429499 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9116286 | 0.72 | TOP2A (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5779740 | 0.72 | ADRB2 (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28709209 | 0.72 | KDM4E (0.73) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6217185 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10591014 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7824025 | 0.69 | KDM4E (0.48) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27879215 | 0.69 | PTGDR2 (0.41) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1414951-A | Drug discharge pump inhibitor | FUNDAMENTAL THERAPEUTICAL INC (US) | 2003-04-30 | — | — | CN | disclosed |