SCHEMBL27573158

SCHEMBL27573158

O=C(CN1C=CC=C(C(=O)NNS(=O)(=O)Cc2ccccc2)C1)Nc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 3/20 0.43
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
CHRNB2 P17787 2/20 0.40
CHRNB4 P30926 2/20 0.40
CHRNA3 P32297 2/20 0.40
CHRNA4 P43681 2/20 0.40
GAA P10253 1/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27457216 0.88 CHRNB2 (0.36) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL27473204 0.86 CHRNB2 (0.46) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL27573462 0.85 GAA (0.43) MAPTALDH1A1GAACA1CA2
SCHEMBL27475349 0.83 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL27591884 0.82 CHRNB2 (0.39) ALDH1A1KMT2APOLBCHRNB2CHRNB4
SCHEMBL27460568 0.81 TPSAB1 (0.36) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL27573192 0.78 SMN1; SMN2 (0.43) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL286819 0.77 MAPT (0.43) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL27573479 0.77 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL27576643 0.74 EPHX1 (0.43) MAPTALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1411800-A Cosmetic composition and method TORENTO PHARMACEUTICAL CO LTD (IN) 2003-04-23 CN claimed
CN-1411809-A Usage and composition of pyridine onium derivative for curing application TORENTO PHARMACEUTICAL CO LTD (IN) 2003-04-23 CN claimed
CN-1411800-A Cosmetic composition and method TORENTO PHARMACEUTICAL CO LTD (IN) 2003-04-23 CN disclosed
CN-1411809-A Usage and composition of pyridine onium derivative for curing application TORENTO PHARMACEUTICAL CO LTD (IN) 2003-04-23 CN disclosed