Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.42 |
| ▸ | CDC42BPB | Q9Y5S2 | 5/20 | 0.42 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556790 | 0.77 | HTR6 (0.42) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL27573339 | 0.77 | HTR6 (0.42) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL7532403 | 0.77 | HTR6 (0.49) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL7532407 | 0.77 | HTR6 (0.49) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL4555174 | 0.74 | HTR6 (0.47) | HTR6MAP4K4HRH4HRH3HSD17B10 | |
| SCHEMBL7532374 | 0.72 | HTR6 (0.48) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL7532372 | 0.72 | HTR6 (0.48) | HTR6ROCK2ROCK1CDC42BPBCDC42BPA | |
| SCHEMBL5103438 | 0.71 | HTR6 (0.50) | HTR6HRH3HSD17B10KDM4EALDH1A1 | |
| SCHEMBL27576667 | 0.69 | HTR6 (0.41) | HTR6HRH4HRH3PKMKDM4E | |
| SCHEMBL3681601 | 0.66 | HRH3 (0.55) | HTR6MAP4K4HRH4HRH3MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335850-A | Quinoline derivatives | SMITHKLINE BEECHMA PLC (GB) | 2002-02-13 | — | — | CN | disclosed |