Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532372 | 1.00 | HTR6 (0.48) | HTR6MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7532403 | 0.81 | HTR6 (0.49) | HTR6MEN1KMT2AMAP4K4HRH4 | |
| SCHEMBL7532407 | 0.81 | HTR6 (0.49) | HTR6MEN1KMT2AMAP4K4HRH4 | |
| SCHEMBL29508860 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL21245856 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL7467872 | 0.77 | EIF2AK2 (0.55) | MEN1KMT2AALDH1A1EIF2AK2HRH4 | |
| SCHEMBL7532954 | 0.76 | ALDH1A1 (0.61) | HTR6ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7532960 | 0.76 | ALDH1A1 (0.61) | HTR6ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7475609 | 0.76 | ALDH1A1 (0.61) | HTR6ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10036373 | 0.75 | MAPT (0.51) | MEN1KMT2ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |