Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068959 | 0.94 | MGLL (0.46) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL14777408 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL30286549 | 0.84 | NR1H2 (0.50) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL9836388 | 0.81 | F2 (0.48) | MGLLALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL5069998 | 0.81 | MGLL (0.36) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL23954215 | 0.79 | HSP90AA1 (0.51) | MGLLALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL5124396 | 0.79 | GRK5 (0.42) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL14275468 | 0.78 | NR1H2 (0.48) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL5110493 | 0.77 | ALDH1A1 (0.40) | NR1H2NR1H3MGLLALDH1A1FAAH | |
| SCHEMBL6629542 | 0.77 | NR1H3 (0.58) | NR1H2NR1H3MGLLALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1468232-A | Heterocyclic sodium/proton exchange inhibitors and method | ����˹�ж�-����˹˹������˾ | 2004-01-14 | — | — | CN | disclosed |