Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068959 | 0.82 | MGLL (0.46) | MGLLNR1H2NR1H3ALDH1A1FAAH | |
| SCHEMBL27575223 | 0.81 | NR1H2 (0.45) | MGLLNR1H2NR1H3ALDH1A1FAAH | |
| SCHEMBL14275471 | 0.79 | PTGS2 (0.44) | NR1H2NR1H3PTGS2MAPT | |
| SCHEMBL9338651 | 0.78 | PTGS2 (0.45) | ALDH1A1MEN1KMT2APTGS2GAA | |
| SCHEMBL9836388 | 0.75 | F2 (0.48) | MGLLALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL14275469 | 0.74 | NR1H2 (0.47) | MGLLNR1H2NR1H3ALDH1A1FAAH | |
| SCHEMBL14051706 | 0.74 | PTGS2 (0.40) | NR1H2NR1H3ALDH1A1PTGS2LMNA | |
| SCHEMBL23954215 | 0.73 | HSP90AA1 (0.51) | MGLLALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL5109381 | 0.73 | MAPK1 (0.39) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL30540066 | 0.72 | PTGS2 (0.48) | ALDH1A1MEN1KMT2APTGS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186847-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-06 | — | — | US | claimed |
| EP-1436296-B1 | PROCESS FOR THE DIRECT PREPARATION OF PYRROLO[3,4-C]PYRROLES | CIBA SC HOLDING AG (CH) | 2006-03-22 | — | — | EP | claimed |
| US-20040249162-A1 | From a pyrrolidinone compound; coloring high molecular weight material | BASF SE (DE) | 2004-12-09 | — | — | US | claimed |
| US-20040171847-A1 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-02 | — | — | US | claimed |
| US-8883889-B2 | Pigment compositions comprising pyrrolo[3,4-c]pyrroles | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-7326793-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326793-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-02-05 | — | — | US | disclosed |
| US-20070117889-A1 | Process for the direct preparation of pyrrolo[3,4-C]pyrroles | RUFFIEUX VINCENT | 2007-05-24 | — | — | US | disclosed |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-7186847-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| EP-1641802-A2 | PROCESS FOR THE PREPARATION OF FUROPYRROLES | Ciba SC Holding AG (CH) | 2006-04-05 | — | — | EP | disclosed |
| EP-1436296-B1 | PROCESS FOR THE DIRECT PREPARATION OF PYRROLO[3,4-C]PYRROLES | CIBA SC HOLDING AG (CH) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005005430-A2 | PROCESS FOR THE PREPARATION OF FUROPYRROLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
| US-20040249162-A1 | From a pyrrolidinone compound; coloring high molecular weight material | BASF SE (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20040171847-A1 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-02 | — | — | US | disclosed |
| EP-1425282-A2 | PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES | Ciba SC Holding AG (CH) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003022848-A2 | PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249162-A1 | From a pyrrolidinone compound; coloring high molecular weight material | PAXBP1, PAX3, PPOX | MGLL 4784/4885NR1H2 4567/4885NR1H3 4611/4885 |
| US-20070117889-A1 | Process for the direct preparation of pyrrolo[3,4-C]pyrroles | PAX3, PPOX, FIP1L1 | MGLL 4560/4885NR1H2 4455/4885NR1H3 4488/4885 |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CCND3, C1S, CCNL2 | MGLL 427/4885NR1H2 1068/4885NR1H3 1167/4885 |
| US-20040171847-A1 | From a pyrrolidinone compound; coloring high molecular weight material | MKI67, PAH, PKLR | MGLL 3323/4885NR1H2 4870/4885NR1H3 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.