Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL39482 | 0.97 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062476 | 0.97 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL29494817 | 0.97 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Phthalic Acid SCHEMBL28406224 | 0.96 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062488 | 0.95 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062829 | 0.95 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL1031053 | 0.93 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Phthalic Acid SCHEMBL840675 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EHMGB1NAPRT | |
| Phthalic Acid SCHEMBL15876041 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHMGB1NAPRT | |
| Toluic Acid SCHEMBL16048346 | 0.83 | ADRB2 (0.42) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1385457-A | Gel composition | PANRICO PARTNERSHIP INC (US) | 2002-12-18 | — | — | CN | disclosed |
| CN-1348815-A | Medicine for preventing and treating coronary heart disease and angina pectoris and its prepn and other use | TIANJIN TIANSHILI PHARMACEUTIC (CN) | 2002-05-15 | — | — | CN | disclosed |