Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL29494817 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062476 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Phthalic Acid SCHEMBL28406224 | 0.99 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062488 | 0.97 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL27575729 | 0.97 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL6062829 | 0.97 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL1031053 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Phthalic Acid SCHEMBL840675 | 0.91 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EHMGB1NAPRT | |
| Phthalic Acid SCHEMBL15876041 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHMGB1NAPRT | |
| Toluic Acid SCHEMBL16048346 | 0.86 | ADRB2 (0.42) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3508 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250332079-A1 | TOPICAL SUNSCREEN | CONCEPT MATRIX SOLUTIONS | 2025-10-30 | — | — | US | claimed |
| US-20240390237-A1 | SOLID COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2024-11-28 | — | — | US | claimed |
| CN-116456956-A | Solid cosmetic material | 株式会社资生堂 | 2023-07-18 | — | — | CN | claimed |
| WO-2022138538-A1 | SOLID COSMETIC | 株式会社 資生堂 | 2022-06-30 | — | — | WO | claimed |
| CN-110549656-B | Preparation method of color printing film for plastic woven bag | 枣阳市东航塑编彩印有限公司 | 2021-12-07 | — | — | CN | claimed |
| US-20210093529-A1 | TOPICAL SUNSCREEN | CONCEPT MATRIX SOLUTIONS | 2021-04-01 | — | — | US | claimed |
| CN-110549656-A | Preparation method of color printing film for plastic woven bag | ZAOYANG DONGHANG PLASTIC WEAVING COLOR PRINTING CO LTD | 2019-12-10 | — | — | CN | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| CN-108025196-A | Water-In-Oil light screening composition with organic sunscreen actives | 莱雅公司 | 2018-05-11 | — | — | CN | claimed |
| EP-3310444-A1 | WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES | L'Oréal (FR) | 2018-04-25 | — | — | EP | claimed |
| US-20020155962-A1 | Nonaqueous hair styling composition and method of use | ANDREW JERGENS COMPANY, THE | 2002-10-24 | — | — | US | claimed |
| US-20020131939-A1 | Hair protection compositions | ROCHE VITAMINS INC. | 2002-09-19 | — | — | US | claimed |
| WO-2001097768-A2 | METHOD OF MAKING ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES | COLGATE-PALMOLIVE COMPANY (US) | 2001-12-27 | — | — | WO | claimed |
| EP-1013466-A2 | Intermediate ink-receiver sheet for transfer printing | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-06-28 | — | — | EP | claimed |
| EP-0705094-B1 | SKIN AND SCALP BARRIER FOR USE WITH HAIR TREATMENT PRODUCTS | CARSON PROD CO (US) | 2000-05-24 | — | — | EP | claimed |
| EP-0705094-A4 | SKIN AND SCALP BARRIER FOR USE WITH HAIR TREATMENT PRODUCTS | AMINCO INC (US) | 1996-08-07 | — | — | EP | claimed |
| EP-0705094-A1 | SKIN AND SCALP BARRIER FOR USE WITH HAIR TREATMENT PRODUCTS | CARSON PRODUCTS COMPANY (US) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000107-A1 | SKIN AND SCALP BARRIER FOR USE WITH HAIR TREATMENT PRODUCTS | AMINCO, INC. (US) | 1995-01-05 | — | — | WO | claimed |
| US-4150114-A | ENHANCED PENETRATION | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4009254-A | UNSYMMETRICAL ETHERS; SUNSCREEN AGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-02-22 | — | — | US | claimed |