Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716615 | 0.81 | TDP1 (0.45) | ALDH1A1TRPA1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL28294225 | 0.79 | KIF11 (0.32) | TRPA1CYP3A4 | |
| SCHEMBL28161117 | 0.75 | BRD4 (0.42) | LMNAPOLB | |
| SCHEMBL8990517 | 0.73 | TDP1 (0.42) | ALDH1A1CYP3A4MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8935677 | 0.73 | ALDH1A1 (0.44) | PMM2MPIALDH1A1TRPA1CYP3A4 | |
| SCHEMBL28672997 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TDP1TSHRPOLB | |
| SCHEMBL11516839 | 0.72 | KMT2A (0.45) | PMM2MPIALDH1A1TRPA1CYP3A4 | |
| SCHEMBL11516843 | 0.72 | KMT2A (0.45) | PMM2MPIALDH1A1TRPA1CYP3A4 | |
| SCHEMBL31264508 | 0.72 | KMT2A (0.45) | PMM2MPIALDH1A1TRPA1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28131657 | 0.71 | TDP1 (0.40) | ALDH1A1CYP3A4MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1356977-A | Glucagon antagonists/inverse agonists | NOVO NORDISK AS (DK) | 2002-07-03 | — | — | CN | disclosed |