Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050007 | 0.80 | CYP3A4 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL1274930 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL29577280 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL639211 | 0.78 | RAB9A (0.52) | ALDH1A1HSD17B10TP53MAPK1HIF1A | |
| SCHEMBL22966239 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL7065478 | 0.78 | CYP3A4 (0.52) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL295740 | 0.78 | MCL1 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL13196361 | 0.78 | DAPK3 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL21087428 | 0.78 | TSHR (0.46) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL12458453 | 0.78 | MEN1 (0.40) | ALDH1A1HSD17B10TSHRTP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348113-B | N-(1-ethyl propyl)-3,4-dimethylaniline continuous production device and method | 绍兴贝斯美化工有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-105348105-B | 4-nitro-o-xylene continuous synthesis system and synthesis method | 绍兴贝斯美化工有限公司 | 2017-04-12 | — | — | CN | claimed |
| CN-106335998-B | The electro-catalysis of anode and cathode synergistic oxidation-ozonation technology method | 北京交通大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-107721804-A | A kind of method for preparing ortho-xylene through 3 nitro ortho-xylenes | 绍兴贝斯美化工股份有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107698437-A | A kind of method for preparing the more formic acid analog derivatives of aromatic hydrocarbons | 朱翠英 | 2018-02-16 | — | — | CN | disclosed |
| CN-107698438-A | A kind of method for preparing the more formic acid analog derivatives of aromatic hydrocarbons | 朱翠英 | 2018-02-16 | — | — | CN | disclosed |
| CN-107698436-A | Method for preparing aromatic polycarboxylic acid derivative | 朱翠英 | 2018-02-16 | — | — | CN | disclosed |
| CN-107698445-A | A kind of method for preparing the more formic acid analog derivatives of aromatic hydrocarbons | 朱翠英 | 2018-02-16 | — | — | CN | disclosed |
| CN-105348113-B | N-(1-ethyl propyl)-3,4-dimethylaniline continuous production device and method | 绍兴贝斯美化工有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-105348105-B | 4-nitro-o-xylene continuous synthesis system and synthesis method | 绍兴贝斯美化工有限公司 | 2017-04-12 | — | — | CN | disclosed |
| US-9550772-B2 | Azaindole derivatives as multi kinase inhibitors | ORIBASE PHARMA (FR) | 2017-01-24 | — | — | US | disclosed |
| US-20100152184-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-06-17 | — | — | US | disclosed |
| US-20100092474-A1 | PHARMACEUTICAL COMBINATIONS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090131501-A1 | Agents Useful for Reducing Amyloid Precursor Protein and Treating Dementia and Methods of Use Thereof | TORREYPINES THERAPEUTICS (US) | 2009-05-21 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| CN-1182111-C | Nitroso compound and use of it as spin catching agent | 兰道克斯实验有限公司 | 2004-12-29 | — | — | CN | disclosed |
| CN-1362405-A | Nitroso compound and use of it as spin catching agent | RANDOV LAB LTD (GB) | 2002-08-07 | — | — | CN | disclosed |
| US-4168279-A | Manufacture of amines of the formula Ar--NH--CH2 --R | BASF AKTIENGESELLSCHAFT (DE) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100092474-A1 | PHARMACEUTICAL COMBINATIONS | HSP90AB1, HEATR6, HEATR1 | ALDH1A1 2281/4885HSD17B10 381/4885TSHR 249/4885 |
| US-20090131501-A1 | Agents Useful for Reducing Amyloid Precursor Protein and Treating Dementia and Methods of Use Thereof | APP, BACE1, PSEN1 | ALDH1A1 2149/4885HSD17B10 2230/4885TSHR 4621/4885 |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | ALDH1A1 678/4885HSD17B10 227/4885TSHR 3980/4885 |
| US-20100152184-A1 | PHARMACEUTICAL COMPOUNDS | RPP30, RPLP1, NR5A1 | ALDH1A1 1780/4885HSD17B10 463/4885TSHR 1425/4885 |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | P2RX7, P2RX1, P2RX2 | ALDH1A1 852/4885HSD17B10 4228/4885TSHR 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.