Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.63 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577211 | 0.90 | CASP3 (0.76) | CASP3PIN1KMT2ACASP1 | |
| SCHEMBL27577210 | 0.90 | CASP3 (0.76) | CASP3PIN1KMT2ACASP1 | |
| SCHEMBL5497705 | 0.84 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL5497707 | 0.84 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL27604454 | 0.84 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL13256276 | 0.82 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL31498750 | 0.82 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL4552562 | 0.82 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL8023154 | 0.82 | CASP3 (0.68) | CASP3PIN1KMT2A | |
| SCHEMBL7402112 | 0.80 | CASP3 (0.58) | CASP3PIN1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162828-A | IMMUNOLOGY; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS; BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-19 | — | — | US | claimed |
| EP-0820464-A2 | CYSTEINE PROTEASE INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1998-01-28 | — | — | EP | claimed |
| WO-1996030395-A2 | CYSTEINE PROTEASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-03 | — | — | WO | claimed |
| US-6162828-A | IMMUNOLOGY; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS; BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |