SCHEMBL27577620

SCHEMBL27577620

CNNC(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 4/20 0.61
CHRNB4 P30926 4/20 0.61
CHRNA3 P32297 4/20 0.61
CHRNA4 P43681 4/20 0.61
BCAT2 O15382 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 4/20 0.53
GAA P10253 3/20 0.53
HTT P42858 3/20 0.53
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7016554 0.88 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL28044689 0.86 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL3223294 0.85 CHRNB2 (0.65) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL27980137 0.81 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL975666 0.79 CHRNB2 (0.67) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL15472559 0.78 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL5665012 0.77 ALDH1A1 (0.61) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL10775382 0.77 POLB (0.52) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL1826396 0.77 CHRNB2 (0.65) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2
SCHEMBL30345390 0.77 CHRNB2 (0.65) CHRNB2CHRNB4CHRNA3CHRNA4BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101171239-B Electroluminescent device CIBA SC HOLDING AG 2013-08-14 CN disclosed
CN-102603688-A Electroluminescent device CIBA SC HOLDING AG 2012-07-25 CN disclosed
CN-1482691-B Display device with anthracene and triazine derivatives LG DISPLAY CO LTD 2010-12-08 CN disclosed
CN-1756451-B OLEDS having improved luminance stability LG PHILIPS LCD CO LTD 2010-10-13 CN disclosed
CN-1756450-B OLEDS having inorganic material containing anode capping layer LG PHILIPS LCD CO LTD 2010-10-13 CN disclosed
CN-100591745-C Electroluminescent device CIBA SC HOLDING AG 2010-02-24 CN disclosed
CN-101184822-A Electroluminescent device CIBA SC HOLDING AG (CH) 2008-05-21 CN disclosed
CN-101171239-A Electroluminescent device CIBA SC HOLDING AG (CH) 2008-04-30 CN disclosed
CN-1950479-A Electroluminescent device CIBA SC HOLDING AG (CH) 2007-04-18 CN disclosed
CN-1886843-A Electroluminescent devices comprising 2-(p-triphenyl)-3-phenyl-pyrazine derivatives CIBA SC HOLDING AG (CH) 2006-12-27 CN disclosed
CN-1867646-A Electroluminescent device CIBA SC HOLDING AG (CH) 2006-11-22 CN disclosed
CN-1845980-A Electroluminescent device CIBA SC HOLDING AG (CH) 2006-10-11 CN disclosed
CN-1756450-A OLEDS having inorganic material containing anode capping layer LG PHILIPS LCD CO LTD (KR) 2006-04-05 CN disclosed
CN-1756451-A OLEDS having improved luminance stability LG PHILIPS LCD CO LTD (KR) 2006-04-05 CN disclosed
CN-1482691-A Display device with anthracene and triazine derivatives �ֹ��� 2004-03-17 CN disclosed