Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 7/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519273 | 0.86 | AGBL2 (0.46) | POLQAKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL13491960 | 0.80 | AKR1C3 (0.40) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL10199570 | 0.80 | AKR1C3 (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16259600 | 0.80 | ANO1 (0.42) | POLQAKR1C3AKR1C2TP53MAPT | |
| SCHEMBL14197184 | 0.79 | IDO1 (0.38) | AKR1C3AKR1C2HIF1A | |
| SCHEMBL14562998 | 0.78 | POLQ (0.56) | POLQICMT | |
| SCHEMBL5461078 | 0.76 | CES2 (0.42) | AKR1C3AKR1C2CYP2D6CYP2C9HIF1A | |
| SCHEMBL6717126 | 0.76 | KDM1A (0.41) | POLQICMT | |
| SCHEMBL25541293 | 0.74 | NR1H2 (0.34) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL12172236 | 0.74 | ALDH1A1 (0.50) | TP53MAPTSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1479716-A | Propionic acid derivatives with PPAR-alpha activating properties | — | 2004-03-03 | — | — | CN | disclosed |