Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740998 | 0.82 | TDP1 (0.39) | ALDH1A1LMNARAB9AL3MBTL1TDP1 | |
| SCHEMBL3656329 | 0.82 | TDP1 (0.39) | ALDH1A1LMNARAB9AL3MBTL1TDP1 | |
| SCHEMBL29053513 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL16493944 | 0.76 | LMNA (0.48) | ALDH1A1LMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL28056341 | 0.75 | KDM4E (0.46) | CFDALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL27991866 | 0.73 | KDM4E (0.34) | CFDALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL29549875 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL2047755 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL29549876 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL4949836 | 0.72 | KDM4E (0.35) | ALDH1A1LMNAKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |
| CN-104718201-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-06-17 | — | — | CN | disclosed |
| CN-1636996-A | Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands | ABBOTT LAB (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1345320-A | Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands | ABBOTT LAB (US) | 2002-04-17 | — | — | CN | disclosed |