Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | BUB1 | O43683 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596406 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10RIPK1 | |
| SCHEMBL2430353 | 0.83 | PTGER4 (0.53) | PTGER4CNR1BUB1POLBMAPT | |
| SCHEMBL14592697 | 0.83 | PTGER4 (0.51) | PTGER4CNR1BUB1POLBMAPT | |
| SCHEMBL5369878 | 0.83 | PTGER4 (0.56) | PTGER4CNR1BUB1POLBMAPT | |
| SCHEMBL27581128 | 0.74 | ITGB1 (0.46) | MAPTKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL27578696 | 0.74 | LMNA (0.41) | PTGER4POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL27578801 | 0.73 | KDM4E (0.48) | POLBMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3428359 | 0.72 | PTGER4 (0.66) | PTGER4CNR1POLBMAPTCNR2 | |
| SCHEMBL2433523 | 0.72 | PTGER4 (0.68) | PTGER4CNR1BUB1CNR2 | |
| SCHEMBL1219481 | 0.71 | PTGER4 (0.88) | PTGER4CNR1POLBKDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471838-C | VLA-4 inhibitors | DAIICHI SEIYAKU CO (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-100396680-C | Vla-4 inhibitors | DAICHI PHARMACEUTICAL CO LTD (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-1699363-A | Vla-4 inhibitors | DAICHI PHARMACEUTICAL CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| CN-1483024-A | Vla-4 inhibitors | ��һ��������ҩ��ʽ���� | 2004-03-17 | — | — | CN | disclosed |