Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42860 | 0.74 | — | — | |
| SCHEMBL29111195 | 0.73 | — | — | |
| Uracil SCHEMBL11666536 | 0.71 | CRBN (0.68) | CRBNSMN1; SMN2MMP2TP53MAPT | |
| Uracil SCHEMBL8202840 | 0.71 | CRBN (0.81) | CRBNMMP2TP53 | |
| Uracil SCHEMBL27454986 | 0.69 | — | — | |
| Phenylisothiocyanate SCHEMBL28818304 | 0.68 | MIF (0.52) | TP53KMT2ATDP1MAPTALDH1A1 | |
| Uracil SCHEMBL479740 | 0.68 | CRBN (0.74) | CRBNSMN1; SMN2MMP2TP53MAPT | |
| Uracil SCHEMBL3798527 | 0.67 | CRBN (1.00) | CRBNSMN1; SMN2MMP2TP53KMT2A | |
| Uracil SCHEMBL5089507 | 0.67 | — | — | |
| Uracil SCHEMBL8235 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1350533-A | novel ECE inhibitors, their preparation and use | BASF AG (DE) | 2002-05-22 | — | — | CN | disclosed |