Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TKT | P29401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615151 | 0.85 | CYP4F2 (0.49) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL8145953 | 0.84 | ALDH1A1 (0.44) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL27347187 | 0.82 | ALDH1A1 (0.42) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL25341019 | 0.81 | LTB4R (0.42) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL29065780 | 0.81 | KAT2B (0.42) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL27429835 | 0.78 | FFAR4 (0.41) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20562605 | 0.77 | KMT2A (0.56) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL10504995 | 0.76 | LTB4R (0.41) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20504803 | 0.76 | KMT2A (0.42) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL27344560 | 0.76 | ALDH1A1 (0.44) | KMT2AMAPTALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100510093-C | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | SALTIGO GMBH (DE) | 2009-07-08 | — | — | CN | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| CN-109734600-B | Synthesis method of chiral beta-hydroxy acid ester compound | 温州大学 | 2020-09-15 | — | — | CN | disclosed |
| CN-109734600-A | A kind of synthetic method of chiral beta carboxylic acid ester type compound | 温州大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-100510093-C | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | SALTIGO GMBH (DE) | 2009-07-08 | — | — | CN | disclosed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | disclosed |